Isuzu Motors Limited is one of the world's largest manufacturers of medium and heavy duty trucks.

Since building its first truck in 1918, Isuzu has sold over 26 million trucks in 64 countries. Isuzu introduced the first air-cooled diesel engine in 1936, the first two-ton low cab forward truck in 1959, the first direct-injection diesel engine in the 1960s, and the first gas engine NPR in 1992. The first American-made F-Series Isuzu truck rolled off the Janesville, Wisconsin assembly line in 1996.

These achievements have helped make Isuzu the #1 selling low cab forward truck in America. The Isuzu F-Series was ranked the best cab-over medium duty truck in customer satisfaction for 1997.